Cautionary optimism: caffeine and Parkinson’s disease risk

نویسندگان

  • Leonard L. Sokol
  • Michael J. Young
  • Alberto J. Espay
  • Ronald B. Postuma
چکیده

Most Parkinson's disease (PD) patients present without known family history and without a diagnosed prodromal phase, underscoring the difficulty of employing primary (neuroprevention) and secondary (neuroprotection) preventions. In cases of monogenic forms, however, potential gene-carrying family members of a proband could engage in neuroprevention, such as exercise or diet modifications, to attenuate the risk of, or delay, disease development. However, a historical lack of recognized disease-modifying interventions has limited clinicians' ability to recommend reliable preventive measures in caring for at-risk populations. We briefly analyze the first retrospective study to examine caffeine consumption and PD risk in a LRRK2 R1628P cohort.

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عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2016